Takasaki Y, Deng JS, Tan EM: A nuclear antigen associated with cell proliferation. Its distribution in synchronized cells. J Exp Med 154: 1899-1909, 1981
Deng JS, Takasaki Y, Tan EM: Nonhistone nuclear antigen reactive with autoantibodies. Immunofluorescent studies of distribution in synchronized cells. J Cell Biol 91: 654-669, 1981
Hashimoto H, Tsuda H, Takasaki Y, Fujimaki N, Suzuki M, Shiokawa Y: Digital ulcers/Gangrene and immunoglobulin classes/complement fixation of anti-dsDNA in systemic lupus erythematosus. J Rheumatol 10: 727-732, 1983
Takasaki Y, Fishwild D, Tan EM: Characterization of proliferating cell nuclear antigen recognized by autoantibodies in lupus sera. J Exp Med 159: 981-992,1984
Takasaki Y, Robinson WA,Tan EM: Proliferating cell nuclear antigen in blastic crisis cells of patients with chronic myeloid leukemia. J Natl Cancer Inst 73: 655-661, 1984
Hashimoto H, Tsuda H, Matsumoto T, Nasu H, Takasaki Y, Shiokawa Y, Hirose S, Terasaki PI, Iwaki Y: HLA antigens associated with systemic lupus erythematosus in Japan. J Rheumatol 12: 919-923, 1985
Hashimoto H, Tsuda H, Takasaki Y, Shiokawa Y: Clinical features and long-term immunosuppressant therapy of SLE patients with nephrotic syndrome. Intern Med 24: 197-198, 1985
Sato C, Nishizawa K, Nakayama T, Nose K, Takasaki Y, Hirose S, Nakamura H: Intranuclear appearance of the phosphorylated form of cytoskeleton-associated350-kDa proteins in U1-ribonucleoprotein regions after growth stimulation of fibrosis. Proc Natl Acad
Sci USA 83: 7287-7291, 1986
Tan EM, Ogata K, Takasaki Y: PCNA/cyclin: A lupus antigen connected with DNA replication. J Rheumatol 14: 89-96, 1987
Hashimoto H, Tsuda H, Hirano T, Takasaki Y, Matsumoto T, Hirose S: Differences in clinical and immunological findings of systemic lupus erythematosus related to age. J Rheumatol 14: 497-501, 1987
Ogata K, Ogata Y, Takasaki Y, Tan EM: Epitopes on proliferating cell nuclear antigen recognized by human lupus autoantibody and murine monoclonal antibody. J Immunol 139: 2942-2946, 1987
Izuma S, Sekino M, Moriuchi T, Koji T, Takasaki Y, Yanaihara C, Yanaihara N, Abe K, Nakane Pk: MODE OF PCNA CYCLIN AND C-MYC ANTIGENS IN REGENERATING RAT LIVERS. Cell Biology 20: 710, 1987
Moriuchi T, Suzuka I, Kadowaki K, Daidoji H, Takasaki Y, Nakane PK: The gene for PCNA( DNA polymerase-delta auxiliary protein) is present in higher plant genomes. Nucleic Acid Res 20: 7-8, 1988
Kasukawa R, Tojo T, Miyawaki S, Yoshida H, Tanimoto K, Nobunaga M, Suzuki T, Takasaki Y, Tamura T: Mixed connective tissue disease- a preliminary diagnostic criteria. Jpn J Rheumatol 1: 263-270, 1988
Suzuka I, Daidoji H, Matsuoka M, Kadowaki K, Takasaki Y, Nakane PK, Moriuchi T: Gene for proliferating-cell nuclear antigen( DNA polymerase d auxiliary protein ) is present in both mammalian and higher plant genomes. Proc Natl Acad Sci USA 86: 3189-3193,
1989
Tokano Y, Murashima A, Takasaki Y, Hashimoto H, Okumura K, Hirose S: Relation between soluble interleukin 2 receptor and clinical findings in patients with systemic lupus erythematosus. Ann Rheum Dis 48: 803-809, 1989
Miyagawa S, Okada N, Takasaki Y, Iida T, Kitano Y , Yoshikawa K, Sakamoto K, Steinberg ML: Expression of proliferating cell nuclear antigen/cyclin in human keratinocytes. J Invest Dermatol 93: 678-681, 1989
Sakamoto M, Takasaki Y, Yamanaka K, Kodama A, Hashimoto H, Hirose S: Purification and characterization of Ki antigen and detection of anti-Ki antibody by enzyme-linked-immunosorbent-assay in patients with systemic lupus erythematosus. Arthritis Rheum
32: 1554-1562, 1989
Nikaido T, Shimada K, Shibata M, Hata M, Sakamoto M, Takasaki Y, Sato C, Takahashi T, Nishida Y: Cloning and nucleotide sequence of cDNA for Ki antigen, a highly conserved nuclear protein detected with sera from patients with systemic lupus erythematosus.
Clin Exp Immunol 79: 209-214, 1990
Murashima A, Takasaki Y, Ohgaki M, Hashimoto H, Hirose S: Activated peripheral blood mononuclear cells detected by murine monoclonal antibodies to proliferating cell nuclear antigen in active lupus patients. J Clin Immunol 10: 28-37, 1990
Negishi K, Stell WK, Takasaki Y: Early histogenesis of the teleostean retina: studies using a novel immunochemical maker, proliferating cell nuclear antigen (PCNA/cyclin). Brain Res Dev Brain Res 55: 121-125, 1990
Takasaki Y, Ohgaki M, Kodama A, Ogata K, Hashimoto H, Shirai T, Hirose H: A sandwich type enzyme-linked immunosorbent assay for proliferating cell nuclear antigen (PCNA/cyclin) using monoclonal antibodies. J Immunol Methods 132: 227-237, 1990
Kuruto R, Nozawa R, Takeishi K, Arai K, Yokota T, Takasaki Y: Myeloid calcium binding proteins: Expression in the differentiated HL-60 cells and detection in sera of patients with connective tissue diseases. J Biochem 108: 650-653, 1990
Hishikawa T,Tokano Y, Sekigawa I, Ando S, Takasaki Y, Hashimoto H, Hirose S, Okumura K, Abe M, Shirai T: HLA-DP+ T cells and deficient Interleukin-2 production in patients with systemic lupus erythematosus. Clin Immunol Immunopathol 55: 285-296, 1990
Yasuma M, Takasaki Y, Matsumoto K, Kodama A, Hashimoto H, Hirose S: Clinical significance of IgG anti-Sm antibodies in patients with systemic lupus erythematosus. J Rheumatol 17: 469-475, 1990
Haneda H, Katabami M, Miyamoto H, Isobe H, Shimizu T, Ishiguro A, Moriuchi T, Takasaki Y, Kawakami Y: The relationship of the proliferating cell nuclear antigen protein to cis-diamminedichloroplatinum(II) resistance of a murine leukemia cell line P338/CDDP.
Oncology 48: 234-238, 1991
Negishi K, Sugawara K, Shinagawa S, Teranishi T, Kuo CH, Takasaki Y: Induction of immunoreactive proliferating cell nuclear antigen(PCNA) in goldfish retina following intravitreal injection with tunicamycin. Brain Res Dev Brain Res 63: 71-83, 1991
Nakamura T, Ebihara I, Takasaki Y, Tomino Y, Koide H: Increased expression of proliferating cell nuclear antigen mRNA in peripheral blood mononuclear cells from patients with IgA nephropathy. Am J Med Sci 302: 214-219, 1991
Negishi K, Stell WK, Teranishi T, Karkhanis A, Owusu-Yaw V, Takasaki Y: Induction of proliferating cell nuclear antigen(PCNA)-immunoreactive cells in goldfish retina following intravitreal injection with 6-hydoxydopamine. Cell Molec Neurobiol 11: 639-659,
1991
Tokano Y, Yasuma M, Harada S, Takasaki Y, Hashimoto H, Okumura K, Hirose SClinical significance of IgG subclass of anti-Sm and U1 ribonucleoprotein antibodies in patients with systemic lupus erythematosus and mixed connective tissue disease. J Clin Immunol
11: 317-325, 1991
Takasaki Y, Yamanaka K, Nikaido T, Shimada K, Shibata M, Hashimoto H, Hirose S: An epitope on Ki antigen recognized by autoantibodies from lupus patients is homologous to SV 40 large T antigen nuclear localization sign. Mol Biol Rep 15: 216, 1991
Kobayashi S, Sugawara M, Takahashi H, Koga K, Taniguchi O, Tsuda H, Hirano T, Takasaki Y, Kumagai Y, Matsumoto T, Hashimoto H, Hirose S: Evaluation of the 1987 reviced ARA criteria for rheumatoid arthritis, a retrospective analysis of Japanese patients
with rheumatoid arthritis. Jpn J Rheumatol 3: 205-216, 1991.
Miura M, Domon M, Sasaki T, Takasaki Y: Induction of proliferating cell nuclear antigen(PCNA) complex formation in quiescent fibroblast from a xeroderma pigmentosum patient. J Cell Physiol 150: 370-376, 1992
Tsurusawa M , Ito M, Zha Z, Kawai S, Takasaki Y, Fujimoto T: Cell-cycle associated expression of proliferating cell nuclear antigen and Ki-67 reactive antigen of bone mallow blast cells in childhood acute leukemia. Leukemia 6: 669-674, 1992
Ito M, Tsurusawa M, Zha Z, Kawai S, Takasaki Y, Fujimoto T: Cell proliferation in childhood leukemia. Comparison of Ki-67 and proliferating cell nuclear antigen immunocytochemical and DNA flow cytometric analysis. Cancer 69: 2176-2182, 1992
Saida T, Dohi S, Sadaki M, Tokuda Y, Ikegawa S, Takasaki Y: Distribution patterns and frequency of proliferating cells in cutaneous keratinocytic neoplasms. Immunohistochemical study with a monoclonal antibody (TOB7) used against proliferating cell nuclear
antigen. J Am Acad Dermatol 26: 744-748, 1992
Takase K, Sawai M, Yamamoto K, Yata J, Takasaki Y, Teraoka H, Tsukada K: Reversible G1 arrest induced by dimethyl sulfoxide in human lymphoid cell line: Kinetics of the arrest and expression of the cell cycle marker proliferating cell nuclear antigen
in Raji cells. Cell Growth Differ 3: 515-521, 1992
Daidoji H, Takasaki Y, Nakane PK: Proliferating cell nuclear antigen (PCNA/cyclin) in plant proliferating cells: Immunohistochemical and quantitative analysis using autoantibodies to PCNA. Cell Biochem Funct 10: 123-132, 1992
Miura M, Domon M, Sasaki T, Kondo S, Takasaki Y: Restoration of proliferating cell nuclear antigen(PCNA) complex formation in xeroderma pigmentosum group. A cells following cis-diamminedichloroplatinum(II) treatment by cell fusion with normal cells. J
Cell Physiol 152: 639-645,1992
Miura M, Domon M, Sasaki T, Kondo S, Takasaki Y: Two types of proliferating cell nuclear antigen(PCNA) complex formation in quiescent normal and xeroderma pigmentosum group A fibroblast following ultraviolet light(uv) irradiation. Exp Cell Res 201: 541-544,
1992
Murashima A, Takasaki Y, Hashimoto H, Hirano T, Hirose S: A case of Raynaud's disease with uterine cancer producing interleukin-6. Clin Rheumatol 11: 410-412, 1992
Hashimoto H, Takasaki Y, Hirokawa K: Systemic lupus erythematosus and congenital anomalies, focusing on neonatal lupus erythematosus and anti-SS-A/SS-B antibodies. Cong Anom 32: 301-307, 1992
Yamanaka K, Takasaki Y, Nishida Y, Shimada K, Shibata M, Hashimoto H: Detection and quantification of anti-Ki antibodies by enzyme-linked immunosorbent assay using recombinant Ki antigen. Arthritis Rheum 35: 667-671, 1992
Tokuda Y, Mukai K, Matsuno Y, Furuya S, Shimosato Y, Takasaki Y, Saida T, Ishihara K: Proliferative activity of cutaneous melanocytic neoplasms defined by a proliferating cell nuclear antigen labeling index. Arch Dermatol Res 284: 319-323, 1992
Kobayashi S, Sugawara M,Takahashi H,Koga K, Tanaguchi O, Tshuda H, Hirano T, Takasaki Y, Kumagai Y, Matsumoto T, Hashimoto H, Hirose S: Evaluation of the 1987 revised ARA criteria for rheumatoid arthritis , a retrospective analysis of Japanese patients
with rheumatoid arthritis. Jpn J Rheumatol 3: 205-216, 1992
Roos G, Landberg G, Huff JP, Houghten R, Takasaki Y, Tan EM: Analysis of the epitopes of proliferating cell nuclear antigen recognized by monoclonal antibodies. Lab Invest 68: 204-210, 1993
Hashimoto H, Sugawara M, Tokano Y, Sakamoto M, Isobe Y, Takasaki Y, Kabasawa K, Hirose S: Follow up study of the changes in the clinical features and prognosis of Japanese patients with systemic lupus erythematosus during the past 3 to 4 decades. J Epidemiol
3: 19-27, 1993
Hasebe T, Mukai K, Yamaguchi N, Ishihara K, Kaneko A, Takasaki Y, Shimosato Y: Prognostic value of immunohistochemical staining for proliferating cell nuclear antigen, p53, and c-erbB-2 in sebaceous gland carcinoma and sweat gland carcinoma: Comparison
with histopathological parameter. Modern Pathol 7: 37-43, 1994
Tokuda Y, Saiga T, Mukai K, Takasaki Y: Growth dynamics of acquired melanocytic nevi. Higher reactivity of proliferating cell nuclear antigen in junctional and compound nevi than intradermal nevi. J Am Acad Dermatol 31: 220-224, 1994
Kawasaki H, Mukai K, Yajima S, Tanaka R, Takayama J, Takasaki Y, Ohira M: Prognostic value of proliferating cell nuclear antigen (PCNA) imunostaining in neuroblastoma. Med Pediatr Oncol 24: 300-304, 1995
Koshino K, Tokano Y, Hishikawa H, Sekigawa I, Takasaki Y, Hashimoto H: Detection of antibodies to HIV-1gp41 and HLA class II antigen-derived peptides in SLE patients. Scand J Rheumatol 34: 288-292, 1995
Sekigawa I, Koshino K, Hishikawa T, Kaneko R, Takasaki Y, Hashimoto H, Hirose S, Inagaki Y, Yamamoto N: Inhibitory effect of the immunosuppressant FK506 on apoptotic cell death induced by HIV-1 gp120. J Clin Immunol 15: 312-317, 1995
Miura M, Sasaki T, Takasaki Y: Characterization of X-ray induced immunostaining of proliferating cell nuclear antigen in human diploid fibroblasts. Radiat Res 145: 75-80, 1996
Takasaki Y, Yano T, Hirokawa K, Takeuchi K, Ando S, Takahashi T, Shimada K, Hashimoto H: An Epitope on Ki antigen recognized by autoantibodies from lupus patients shows homology with SV 40 large T antigen nuclear localization signal. Arthritis Rheum 39:
855-862,1996
Miura M, Nakamura S, Sasaki T, Takasaki Y, Shiomi T, Yamaizumi M: Roles of XPG and XPF/ERCC1 endonucleases in UV-induced immunostaining of PCNA in fibroblasts. Exp Cell Res 226: 126-132, 1996
Kobayashi S, Tamura N, Ichikawa G, Takasaki Y, Hashimoto H: Reactive arthritis induced by pseudomonas aeruginosa. Clin Rheumatol 15: 516-517, 1996
Tokano Y, Tsujimura M, Sakai K, Takasaki Y, Hashimoto H: Central nervous system involvement of patients with systemic lupus erythematosus. Jpn J Rheumatol 6: 239-251, 1996
Tokano Y, Miyake S, Kayagaki N, Nozawa K, Morimoto S, Azuma M, Yagita H, Takasaki Y, Okumura K, Hashimoto H: Soluble Fas molecule in the serum of patients with systemic lupus erythematosus. J Clin Immunol 16: 261-265, 1996
Morimoto S, Tokano Y, Takasaki Y, Hashimoto H: Relationship between the level of soluble CD4, CD8 and CD23 molecules in sera and clinical manifestations and laboratory data in patients with systemic lupus erythematosus. Jpn J Rheumatol 6: 301-307, 1996
Kobayashi S, Tamura N, Akimoto T, Ichikawa G, Xi G, Takasaki Y, Hashimoto H: Reactive arthritis induced by tonsillitis. Acta Otolaryngol (Stockh) 523: 206-211, 1996
Takeuchi K, Kaneda K, Kawakami I, Takasaki Y, Hashimoto H: Autoantibodies recognizing proteins copurified with PCNA in patients with connective tissue diseases. Mol Biol Rep 23: 243-246, 1996
Tokano Y, Morimoto S, Endo S, Hayashi F, Harada S, Kobayashi S, Tsuda H, Azuma M, Takasaki Y, Kyogoku Y, Arata Y, Okumura K, Hashimoto H, Hirose S: A hidden IgG2 in patients with arthritis as detected by nuclear magnetic resonance. J Rheumatol 24:275-281,1997
Smolen JS, Fritzler MJ, Gordon T, Hardin J, Kalden JR, Mainni RN, Reeves W, Reichlin M, Rothfield N, Takasaki Y, van Venrooji W, Tan EM: Reference sera for anti-nuclear antibodies II. Further definition of autoantibody specificities in international ANA
reference sera by immunofuluorescence and western blotting. Arthritis Rheum 40: 413-418,1997
Kobayashi S, Sekiya S, Niizuma N, Sakamoto M, Tamura N, Akimoto T, Takasaki Y, Hashimoto H: Successful treatment of severe Reiter's syndrome with etretinate. Jpn J Rheumatol 7: 47-54,1997
Tan EM, Feltkamp TEW, Smolen JS, Bucher B, Dawkins R, Fritzler MJ, Gordon T, Hardin J, Kalden JR, Lahita RG, Mainni RN, MacDougal JS, Rothfield NF, Smeenk RJ, Takasaki Y, Wiik A, Wilson MR, Koziol JA: Range of antinuclear antibodies in " Healthy" individuals.
Arthritis Rheum 40: 1601-1611, 1997
Tokano Y, Morimoto S, Hishikawa H, Murashima A, Abe M, Sekigawa I, Takasaki Y, Hashimoto H, Okumura K, Shirai T, Hirose S: Subsets of activated T cells in patients with systemic lupus erythematosus-the relation to cell cycle. Scand J Rheumatol 26: 37-42,
1997
Hishikawa T, Ogasawara H, Kaneko H, Shirasawa T, Matsuura Y, Sekigawa I, Takasaki Y, Hashimoto H, Hirose S, Handa S, Nagasawa R, Maruyama N: Detection of antibodies to a recombinant gag protein derived from human endogenous retrovirus clone 4-1 in autoimmune
diseases. Viral Immunol 10: 137-147, 1997
Takahashi T, Takasaki Y, Yamanaka K, Takeuchi K, Oshimi K, Hashimoto H: Detection of proliferating cell nuclear antigen (PCNA) in peripheral blood mononuclear cells and sera of patients with malignant lymphoma. Leuk Lymphoma 28: 113-125, 1997
Haruta K, Kobayashi S, Hirose S, Horiai A, Ohyanagi M, Tanaka M, Kawano T, Shirai T, Takasaki Y, Hashimoto H: Monoclonal anti-cardiolipin antibodies from New Zealand black x New Zealand white F1 mice react to thrombomodulin. J Immunol 160: 253-258, 1998
Takasaki Y, Ogaki M, Abe K, Takeuchi K, Ando S, Tokano Y, Kobayashi S, Sekigawaj I, Tsuda H, Hashimoto H: The expression of costimulatory molecule CD80 on peripheral blood T cells in patients with systemic lupus erythematosus. J Rheumatol 25: 1085-1091,
1998
Ogiwara T, Ando S, Kobayashi H, Hishikawa T, Takasaki Y, Hashimoto H: A case of intestinal Behcet disease in association with HLA-27 and HLA-B51. Jpn J Rheumatol 8: 89-92, 1998
Hashimoto H, Yamanaka K, Tokano Y, Iida N, Takasaki Y, Kabasawa K, Nishimura Y: HLA-DRB1 alles and b2 glycoprotein 1-dependent anticardiolipin antibodies in Japanese patients with systemic lupus erythematosus. Clin Exp Rheumatol 16: 423-427, 1998
Seki M, Ushiyama C, Seta N, Abe K, Fukazawa T, Asakawa J, Takasaki Y, Hashimoto H: Apoptosis of lymphocytes induced by glucocorticoids and relationship to therapeutic efficacy in patients with systemic lupus erythematosus. Arthritis Rheum 41: 823-830,
1998
Tsune I, Ando S, Hishikawa T, Takasaki Y, Hashimoto H: A case of mixed connective tissue disease associated with macrovascular lesions in the upper and lower extremities. Jpn J Rheumatol 8: 439-444, 1998
Lee S, Kaneko H, Sekigawa I, Tokano Y, Takasaki Y, Hashimoto H: Circulating IL-6 in systemic lupus erythematosus patients. Brit J Rheumatol 37: 1334-1337, 1998
Abe K, Takasaki Y, Ushiyama C, Asakawa, J, Fukazawa T, Seki M, Hirashima M, Ogaki M, Hashimoto H: Expression of CD80 and CD86 on peripheral blood T lymphocytes in patients with systemic lupus erythematosus. J Clin Immunol 19: 58-66, 1999
Shiroki K, Isoyama T, Kuge S, Ishii T, Ohmi S, Hata S, Suzuka K, Takasaki Y, Nomoto A: Intracellular redistribution of truncated La protein produced by Poliovirus 3Cpro-mediated cleavage. J Virol 73: 2193-2200, 1999
Takasaki Y, Abe K, Tokano Y, Hashimoto H: The expression of LFA-1, ICAM-1, CD80 and CD86 molecules in lupus patients: Implication for immunotherapy. Intern Med 38: 175-177, 1999
Tokano Y, Morimoto S, Kaneko H, Amano H, Nozawa, Takasaki Y, Hashimoto H: The level of Interleukin-12 in the sera of patients with systemic lupus erythematosus-Relation to Th-1and Th-2 derived cytokines. Clin Exp Immunol 116: 169-173, 1999
Murashima A, Sekigawa I, Takasaki Y, Hashimoto H: Cyclosporine treatment of advanced interstitial pneumonitis associated with systemic sclerosis. Jpn J Rheumatol 9: 95-99, 1999
Tan EM, Smolen JS, MacDougal JS, Bucher BT, Conn D, Feltkamp TEW, Dawkins R, Fritzler MJ, Gordon T, Hardin JA, Kalden JR, Lahita RG, Mainni RN, Rothfield NF, Smeenk R, Takasaki Y, von Venooij WJ, Wiik A, Wilson M, Koziol JA: A clinical evaluation of enzyme
immunoassay for detection of antinuclear autoantibodies of defined specificities. I. Precision, Sensitivity and Specificity. Arthritis Rheum 42: 455-464, 1999
Tokano Y, Amano H, Takai S, Ymanaka K, Sugawara M, Takasaki Y, Hashimoto H: Long term prognosis in lupus nephritis: Relation to the renal biopsy data, therapy and the grade of remission. Jpn J Rheumatol 9: 135-145, 1999
Isoyama T, Kamoshita N, Yasui K, Iwai A, Shiroki K, Toyoda H, Yamada A, Takasaki Y, Nomoto A: Lower concentration of La protein required for internal ribosome entry on hepatitis C virus RNA than on poliovirus RNA. J Gen Virol 80: 2319-2327, 1999
Kaneko H, Ogasawara H, Naito T, Akimoto H, Lee S; Hishikawa T, Sekigawa I, Tokano Y, Takasaki Y, Hirose S, Hashimoto H: Circulating levels of beta-chemokines in systemic lupus erythematosus. J Rheumatol 26: 568-573, 1999
Nishimaki T, Aotsuka S, Kondo H, Ymamoto K, Takasaki Y, Sumiya M, Yokohari R: Immunological analysis of pulmonary hypertension in connective tissue disease. J Rheumatol 26: 2357-2362, 1999
Ogasawara H, Kaneko H, Hishikawa T, Sekigawa I, Takasaki Y, Hashimoto H, Hirose S, Kaneko H, Maruyama N: Molecular mimicry between human endogenous retrovirus clone 4-1 and HLA class I antigen: with reference to the pathogenesis of systemic lupus erythematosus.
Rheumatology 38: 1163-1164, 1999
Tanaka M, Kobayashi S, Kumgai Y, Ebitsuka T, Matsumoto T, Takasaki Y, Hashimoto H: Scleroderma: report of a case. Modern Rheumatol 10: 51-53, 2000
Amano H, Morimoto S, Kaneko H, Tokano Y, Takasaki Y, Hashimoto H: Effect of intravenous cyclophosphamide in systemic lupus erythematosus: relation to lymphocyte subsets and activation markers. Lupus 9: 26-32, 2000
Akimoto T, Kobayashi S, Tamura N, Bando H, Ikeda M, Fujii T, Horirano T, Takasaki Y, Hashimoto H: Sjogren's syndrome associated with multiple myeloma of the IgA k-type. Modern Rheumatol 10: 110-113, 2000
Takasaki Y, Kogure T, Takeuchi K, Kaneda K, Yano T, Hirokawa K, Hirose S, Shirai T, Hashimoto H: Reactivity of anti-proliferating cell nuclear antigen (PCNA) murine monoclonal antibodies to the PCNA multiprotein complexes involved in cell proliferation.
J Immunol 166: 4780-4787, 2001
Haruta K, Kobayashi S,Tajima M, Sakai A, Tamura N, Bnado H, Hara M, Kawashima S, Takasaki Y, Hashimoto H: Effect of immune complexes in serum from patients with rheumatoid vasculitis on the expression of cell adhesion molecules on polymorphonuclear cells.
Clin Exp Rheumatol 19: 59-68, 2001
Fujinaga H, Takeuchi K, Kaneda K, Takasaki Y, Hashimoto H: Analysis of autoantibodies to cell cycle associated antigens. Modern Rheumatol 11: 221-229, 2001
Kawaguchi R, Takasaki Y, Hirokawa K, Takeuchi K, Kaneda K, Hashimoto H: Characterization of autoantibodies to 60-kD SS-A, 52-kD SS-A, and SS-B in Japanese lupus mothers with neonatal lupus syndrome. Jpn J Clin Immunol 24: 291-302, 2001
Suzuki J, Morimoto S, Amano H, Tokano Y, Takasaki Y, Hashimoto H: The serum levels of interleukin-15 in patients with rheumatic diseases. J Rheumatol 28: 2389-2391, 2001
Tan E M, Smolen JS, McDougal J S, Klippel JH, Fritzler M J, Gordon T, Hardin J A, Kalden J R, Lahita R G, Maini R N Rothfield N F, Takasaki Y, Wiik A, Wilson M R, Koziol J A. A critical evaluation of enzyme immunoassay kits for the detection of antinuclear
antibodies of defined specificities. II. Potential for quantitation of antibody content. J Rheumatol 29: 68-74, 2002
Yano T, Takasaki Y, Takeuchi K, Hirokawa K, Yamanaka K, Hashimoto H: Anti-Ki antibodies recognize an epitope homologous with SV40 nuclear localization signal-Clinical significance and reactivities in various immunoassays. Modern Rheumatol 12: 50-55, 2002
Hirokawa K, Takasaki Y, Takeuchi K, Kaneda K, Ikeda K, Hashimoto H: Anti-TS1-RNA: Characterization of a novel antibody against the sequence-specific RNA by a random RNA selection in patients with Sjogren's syndrome. J Rheumatol 29: 931-937, 2002
Takasaki Y, Kaneda K, Yamada H, Ikeda, Ikeda K, Matsushita M, Matsudaira R,Takeuchi K, Shindo N, Murayama K, Hashimoto H: Autoimmune response to glycelaldehyde-3-phosphate dehydrogenase (GAPDH) is strongly associated with its cellular finction in lupus
patients. Autoantigens, Autoantibodies, Autoimmunity 3:93-115, 2002
Takasaki Y, AndoS, Matsumoto K,Yamada H, Ikeda K, Nawata M, Matsushita M, Matsudaira R, Kaneda K, Takeuchi K, Tokano Y, Hashimoto H: Activated peripheral blood mononuclear cells detected in lupus patients using cDNA coding for proliferating cell nuclear
antigen. Modern Rheumatol 12: 239-245, 2002
Sugimoto K, Morimoto S, Kaneko H, Nozawa K, Tokano Y, Takasaki Y, Hashimoto H: Decreased IL-4 producing CD4 + T cells in patients with systemic lupus erythematosus-Relation to IL-12R expression. Autoimmunity 35: 381-387, 2002
Kogure T, Takasaki Y,Takeuchi K,Yamada H, Nawata M,Matsushita M,Matsudaira R, Kaneda K,Terasawa K, Hashimoto H: Autoimmune responses to proliferating cell nuclear antigen multiprotein complexes involved in cell proliferation are strongly associated with
their structure and biologic function in patients with systemic lupus erythematosus. Arthritis Rheum 46: 2946-56, 2002
Murakami A, Kojima K, Ohya K, Imamura K, Takasaki Y: A new conformational epitope generated by the binding of recombinant 70-kd and U1 RNA to anti-U1 RNP autoantibodies in sers from patients with mixed connective tissue disaese. Arthritis Rheum 46: 3273-3282,
2002
Tokano Y, Ogasawara H, Ando S, Fujii T, Kaneko H, Tamura N, Yano T, Hirokawa K, Fukazawa T, Murashima A, Kobayashi S, Sekigawa I, Takasaki Y, Iida N, Hashimoto H: Cyclosporine A therapy for interstitial pneumonitis associated with rheumatic diseases.
Modern Rheumatol 12: 305-310, 2002
Takasaki Y, Kaneda K, Taakeuchi K, Matsudaira R, Mataushita M, Yamada H, Nawata M, Ikeda K, Kaneda K, Hashimoto H: Analysis of structure of proteasome-PCNA multiprotein complex and its autoimmune response in lupus patients. Ann N Y Acad Sci 987: 316-318,
2003
Kusaoi M, Fukazawa T, Hirashima M, Morita Y, Yamaji C, Takai S, Takasaki Y, Hashimoto H: A case of inclusion body myositis with systemic sclerosis. Modern Rheumatol 13: 87-89, 2003
Ikeda K, Hirokawa K, Takasaki Y,Takeuchi K, Hashimoto H: Clinical significance of antibodies to TS1-RNA in patients with mixed connective tissue disease. J Rheumatol 30: 998-1005, 2003
Matsudaira R, Takeuchi K, Takasaki Y, Yano T, Matsushita M, Hashimoto H:Relationships between autoantibody responses to deletion mutants of ki antigen and clinical manifestations of lupus. J Rheumatol 30: 1208-1214, 2003
Suzuki K, Sawada T, Murakami A, Matsui T, Tohma S, Nakazono K,Takemura M, Takasaki Y, Mimori T, Yamamoto K: High diagnostic performance of ELISA detection of antibodies to citrullinated antigens in rheumatoid arthritis. Scand J Rheumatol 32: 197-204,
2003
Bando H, Kobayashi S, Matsumoto T, Tamura N, Yamanaka K, Yamaji C, Takasaki C, Takasaki Y, Hashimoto H: Acute acalculous cholecystitis induced by mesenteric inflammatory veno-occulusive disease (MIVOD) in systemic lupus erythematosus. Clin Rheumatol 22:
447-449, 2003
Fritzler MJ, Wiik A, Tan EM, Smolen JS, McDougal JS, Chan EK, Gordon TP, Hardin JA, Kalden JR, Lahita RG, Maini RN, Reeves WH, Rothfield NF, Takasaki Y, Wilson M, Byrd MG, Slivka L, Koziol JA: A Critical Evaluation of Enzyme Immunoassay Kits for Detection
of Antinuclear Autoantibodies of Defined Specificities. III. Comparative Performance Characteristics of Academicnd Manufacturers' Laboratories. J Rheumatol 30: 2374-2381, 2003
Murashimal A, Fukazawa T, Hirashima M, Takasaki Y, Oonishi M, Niijima S, Yamashiro Y, Yamataka A, Miyano T, Hashimoto H: Long term prognosis of children born to lupus patients. Ann Rheum Dis 63: 50-53, 2004
Matsushita M, Takasaki Y, Takeuchi K, Yamada H, Matsudaira R, Hashimoto H: Autoimmune response to proteasome activator 28a in patients with connective tissue diseases. J Rheumatol 31: 252-259, 2004
Watanabe A, Kodera M, Sugiura K, Usuda T, Tan EM, Takasaki Y, Tomita Y, Muro Y. Anti-DFS70 antibodies in 579 healthy hospital workers. Arthritis Rheum 50: 892-900, 2004
Takasaki Y, Kaneda K, Matsushita M, Yamada H, Nawata M, Matsudaira R, Asano M, Mineki R, Shindo N, Hashimoto H: Glyceraldehyde 3-phosphate dehydrogenase is a novel autoantigen leading autoimmune responses to proliferating cell nuclear antigen multiprotein
complexes in lupus patients. Int Immunol 16: 1295-1304, 2004
Kaneda K, Takasaki Y, Takeuchi K, Yamada H, Nawata M, Matsushita M, Matsudaira R, Ikeda K, Yamanaka K, Hashimoto H: Autoimmune response to proteins of proliferating cell nuclear antigen (PCNA) multiprotein complexes in patients with connective tissue
diseases. J Rheumatol 31: 2142-2150, 2004
Takasaki Y, Yamanaka K, Takasaki C, Matsushita M, Yamada H, Nawata M, Matsudaira R, Ikeda K, Kanneda K, Hashimoto H: Anti-cyclic citrullinated peptide antibodies in patients with mixed connective tissue disease. Modern Rheumatol 14: 367-375, 2004
Matsuda Y, Tsuda H, Takasaki Y, Hashimoto H: Double filtration plasmapheresis for the treatment of a rheumatoid arthritis patient with extremely high level of c-reactive protein.Ther Apher Dial 8: 404-408, 2004
Tokano Y, Morimoto S, Amano H, Kawanishi T, Yano T, Tomyo M, Sugawara M, Kobayashi S, Tsuda T, Takasaki Y, Hashimoto H: The relation between initial clinical manifestation and long term prognosis of patients with systemic lupus erythematosus. Modern Rheumatol
15: 275-282, 2005
Mahler M, Kessenbrock K, Szmyrka M, Takasaki Y, Garcia-De La Torre I, Shoenfeld Y, Hiepe F, Shun-le C, von Muhlen CA, Locht H, Hopfl P, Wiik A, Reeves W, Fritzler MJ: International multicenter evaluation of autoantibodies to ribosomal P proteins. Clin
Vaccine Immunol 13: 77-83, 2006
Suzuki J, Nakano S, Nakairi Y, Mitsuo A, Amano H, Morimoto S, Tokano Y, Takasaki Y: CD19/22 balance relates to improvement of disease activity in systemic lupus erythematosus. Mod Rheumatol 16: 235-238, 2006
Akagawa M, Ito S, Toyoda K, Ishii Y, Tatsuda E, Shibata T, Yamaguchi S, Kawai Y, Ishino K, Kishi Y, Adachi T, Tsubata T, Takasaki Y, Hattori N, Matsuda T, Uchida K: Bispecific abs against modified protein and DNA with oxidized lipids. Proc Natl Acad Sci
U S A 103: 6160-6165, 2006
Mitsuo A, Morimoto S, Nakiri Y, Suzuki J, Kaneko H, Tokano Y, Tsuda H, Takasaki Y, Hashimoto H: Decreased CD161+CD8+ T cells in the peripheral blood of patients suffering from rheumatic diseases. Rheumatology 45: 1477-1484, 2006
Morita Y, Fukazawa T, Hirashima M, Kaga K, Kusaoi M, Morita T, Touyama S, Morita K, Takasaki Y, Hashimoto H: The effect of methotrexate (MTX) on expression of signalling lymphocytic activation molecule (SLAM) in patients with rheumatoid arthritis (RA)
and its role in the regulation of cytokine production. Scand J Rheumatol 35: 268-272, 2006
Onuma S, Yamaji K, Kempe K, Ogasawara M, Ogawa T, Yang K, Kanai M, Tsuda H, Takasaki Y: Investigation of the clinical effect of large volume leukocytapheresis on methotrexate-resistant rheumatoid arthritis. Ther Apher Dial 10: 404-411, 2006
Yamaji K, Onuma S, Yasuda M, Kanai Y, Tsuda H, Takasaki Y: Fluctuations in peripheral blood leukocyte and platelet counts and leukocyte recruitment with large volume leukocytapheresis in healthy volunteers. Ther Apher Dial 10: 396-403, 2006
Toyoda K, Nagae R, Akagawa M, Ishino K, Shibata T, Ito S, Shibata N, Yamamoto T, Kobayashi M, Takasaki Y, Matsuda T, Uchida K: Protein-bound 4-hydroxy-2-nonenal: an endogenous triggering antigen of anti-DNA response. J Biol Chem 282: 25769-25778, 2007
Yoshidome Y, Morimoto S, Tamura N, Kobayashi S, Tsuda H, Hashimoto H, Takasaki Y: A case of polymyositis complicated with myasthenic crisis. Clin Rheumatol 26: 1569-1570, 2007
Nakiri Y, Minowa K, Suzuki J, Mitsuo A, Amano H, Morimoto S, Tokano Y, Takasaki Y: Expression of CD22 on peripheral B cells in patients with rheumatoid arthritis: relation to CD5-positive B cells. Clin Rheumatol 26: 1721-1723, 2007
Negishi M, Saraya A, Miyagi S, Nagao K, Inagaki Y, Nishikawa M, Tajima S, Koseki H, Tsuda H, Takasaki Y, Nakauchi H, Iwama A: Bmi1 cooperates with Dnmt1-associated protein 1 in gene silencing. Biochem Biophys Res Commun 353: 992-998, 2007
Nakano S, Morimoto S, Suzuki J, Mitsuo A, Nakiri Y, Katagiri A, Nozawa K, Amano H, Tokano Y, Hashimoto H, Takasaki Y : Down-regulation of CD72 and increased surface IgG on B cells in patients with lupus nephritis. Autoimmunity 40: 9-15, 2007
Kawasaki A, Tsuchiya N, Ohashi J, Murakami Y, Fukazawa T, Kusaoi M, Morimoto S, Matsuta K, Hashimoto H, Takasaki Y, Tokunaga K: Role of APRIL (TNFSF13) polymorphisms in the susceptibility to systemic lupus erythematosus in Japanese. Rheumatology 46: 777-782,
2007
Yoshidome Y, Morimoto S, Tamura N, Kobayashi S, Tsuda H, Hashimoto H, Takasaki Y: A case of primary antiphospholipid antibody syndrome presenting dysfunctional uterine bleeding and cerebral infarction. Mod Rheumatol 17: 251-252, 2007
Yamaji K, Yasuda M, Yang KS, Kanai Y, Yamaji C, Kawanishi T, Toumyo M, Funabiki K, Tsuda H, Takasaki Y: A case of very-late-onset systemic lupus erythematosus. Mod Rheumatol 17: 441-444, 2007
Morimoto S, Nakano S, Watanabe T, Tamayama Y, Mitsuo A, Nakiri Y, Suzuki J, Nozawa K, Amano H, Tokano Y, Kobata T, Takasaki Y: Expression of B-cell activating factor of the tumor necrosis factor family (BAFF) in T cells in Active Systemic Lupus Erythematosus.
The Role of BAFF in T cell-dependent B cell Pathogenic Autoantibody Production. Rheumatology 46: 1083-1086, 2007
Tamura N, Matsudaira R, Hirashima M, Ikeda M, Tajima M, Nawata M, Morimoto S, Kaneda K, Kobayashi S, Hashimoto H, Takasaki Y: Two Cases of Refractory Wegener's Granulomatosis Successfully Treated with Rituximab. Internal Med 46: 409-414, 2007
Matsumoto T, Yamasaki S, Arakawa A, Abe K, Abe H, Kon K, Kobayashi S, Takasaki Y: Exposure to a high total dosage of glucocorticoids produces non-alcoholic steatohepatits. Pathol Int 57: 388-389, 2007
Inui A, Ogasawara H, Naito T, Sekigawa I, Takasaki Y, Hayashida Y, Takamori K, Ogawa H: Estrogen receptor expression by peripheral blood mononuclear cells of patients with systemic lupus erythematosus. Clin Rheumatol 26: 1675-1678, 2007
Njaman W, Iesaki T, Iwama Y, Takasaki Y, Daida H: Serum uric acid as a prognostic predictor in pulmonary arterial hypertension with connective tissue disease. Int Heart J 48: 523-532, 2007
Nakano S, Morimoto S, Suzuki J, Nozawa K, Amano H, Tokano Y, Takasaki Y : Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus. Rheumatology 47: 145-149, 2008
Watanabe T, Suzuki J, Mitsuo A, Nakano S, Tamayama Y, Katagiri A, Amano H, Morimoto S, Tokano Y, Takasaki Y : Striking alteration of some populations of T/B cells in systemic lupus erythematosus: relationship to expression of CD62L or some chemokine receptors.
Lupus 17: 26-33, 2008
Nozawa K, Fritzler MJ, Ikeda K, Takasaki Y, Satoh M, Chan EKL: Differential Anti-Golgi Complex Autoantibody Production Following Murine Lactate Dehydrogenase-Elevating Virus Infection. Immunopharmacol Immunotoxicol 30: 13-25, 2008
Kawasaki A, Kyogoku C, Ohashi J, Miyashita R, Hikami K, Kusaoi M, Tokunaga K, Takasaki Y, Hashimoto H, Behrens TW, Tsuchiya N: Association of IRF5 polymorphisms with systemic lupus erythematosus in a Japanese population: Support for a crucial role of
intron 1 polymorphisms. Arthritis Rheum 58: 826-834, 2008
Mamegano K, Kuroki K, Miyashita R, Kusaoi M, Kobayashi S, Matsuta K, Maenaka K, Colonna M, Ozaki S, Hashimoto H, Takasaki Y, Tokunaga K, Tsuchiya N: Association of LILRA2 (ILT1, LIR7) splice site polymorphism with systemic lupus erythematosus and microscopic
polyangiitis. Genes Immun 9: 214-223, 2008
Katagiri A, Ando T, Kon T, Yamada M, Iida N, Takasaki Y: Cavitary lung lesion in a patient with systemic lupus erythematosus: an unusual manifestation of cytomegalovirus pneumonitis. Mod Rheumatol 18: 285-289, 2008
Sekigawa I, Kaneda K, Kaneko H, Takasaki Y, Takamori K, Ogawa H: Detection of serum IgE class anti-SSA antibodies in mothers with foetal loss. Rheumatol Int 28: 623-626, 2008
Kawasaki M, Kaneda K, Kaneko H, Sekigawa I, Takasaki Y, Ogawa H: Two cases of dermatomyositis associated with interstitial pneumonia: a comprehensive study of gene expression. Clin Exp Rheumatol 26: 379-380, 2008.
Sekigawa I, Yanagida M, Iwabuchi K, Kaneda K, Kaneko H, Takasaki Y, Jung G, Sone S, Tanaka Y, Ogawa H, Takamori K: Protein biomarker analysis by mass spectrometry in patients with rheumatoid arthritis receiving anti-tumor necrosis factor-alpha antibody
therapy. Clin Exp Rheumatol 26: 261-267, 2008.
Amano H, Furuhata N, Tamura N, Tokano Y, Takasaki Y : Hypocomplementemic urticarial vasculitis with Jaccoud's arthropathy and valvular heart disease: case report and review of the literature. Lupus 17: 837-841, 2008
Yamaji K, Kim YJ, Tsuda H, Takasaki Y : Long-term Clinical Outcomes of Synchronized Therapy With Plasmapheresis and Intravenous Cyclophosphamide Pulse Therapy in the Treatment of Steroid-resistant Lupus Nephritis. Ther Apher Dial 12: 298-305, 2008
Katagiri A, Morimoto S, Nakiri Y, Nakano S, Mitsuo A, Suzuki J, Amano H, Nozawa K, Asano M, Tokano Y, Hashimoto H, Takasaki Y: Decrease in CD4+CD25+ and CD8+CD28+ T cells in interstitial pneumonitis associated with rheumatic disease. Mod Rheumatol 18:
562-569, 2008
Nozawa K, Fritzler MJ, Takasaki Y, Wood MR, Chan EKL: Co-clustering of Golgi complex and other cytoplasmic organelles to crescentic region of half-moon nuclei during apoptosis. Cell Biol Int 33:148-157, 2009
Nozawa K, Ikeda K, Satoh M, Reeves WH, Stewart CM, Li YC, Yen TJ, Rios RM, Takamori K, Ogawa H, Sekigawa I, Takasaki Y, Chan EK: Autoantibody to NA14 is an independent marker primarily for Sjogren's syndrome. Front Biosci 14: 3733-3739, 2009
Morimoto S, Tokano Y, Nakano S, Watanabe T, Tamayama Y, Mitsuo A, Suzuki J, Kaneko H, Sekigawa I, Takasaki Y: Chemoattractant mechanism of Th1 cells in class III and IV lupus nephritis. Autoimmunity 42: 143-149, 2009
Ito I, Kawasaki A, Ito S, Hayashi T, Goto D, Matsumoto I, Tsutsumi A, Hom G, Graham RR, Takasaki Y, Hashimoto H, Ohashi J, Behrens TW, Sumida T, Tsuchiya N: Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus
in a Japanese population. Arthritis Rheum 60: 553-558, 2009
Ogasawara M, Oda K, Yamaji K, Takasaki Y: Polyarticular septic arthritis with bilateral psoas abscesses following acupuncture. Acupunct Med 27: 81-82, 2009
Santiago-Raber ML, Amano H, Amano E, Baudino L, Otani M, Lin Q, Nimmerjahn F, Verbeek JS, Ravetch JV, Takasaki Y, Hirose S, Izui S: Fcgamma receptor-dependent expansion of a hyperactive monocyte subset in lupus-prone mice. Arthritis Rheum 60: 2408-2417,
2009
Matsushita M, Matsudaira R, Ikeda K, Nawata M, Tamura N, Takasaki Y: Anti-proteasome activator 28α is a novel anti-cytoplasmic antibody in patients with systemic lupus erythematosus and Sjögren's syndrome. Mod Rheumatol 19: 622-628, 2009
Nozawa K, Fujishiro M, Kawasaki M, Kaneko H, Iwabuchi K, Yanagida M, Suzuki F, Miyazawa K, Takasaki Y, Ogawa H, Takamori K, Sekigawa I: Connective tissue growth factor promotes articular damage by increased osteoclastogenesis in patients with rheumatoid
arthritis. Arthritis Res Ther 11: R174, 2009
Kawasaki M, Sekigawa I, Nozawa K, Kaneko H, Takasaki Y, Takamori K, Ogawa H: Changes in the gene expression of peripheral blood mononuclear cells during the menstrual cycle of females is associated with a gender bias in the incidence of systemic lupus
erythematosus. Clin Exp Rheumatol 27: 260-266, 2009
Nozawa K, Kaneko H, Itoh T, Katsura Y, Noguchi M, Suzuki F, Takasaki Y, Ogawa H, Takamori K, Sekigawa I: Synchronous malignant B-cell lymphoma and gastric tubular adenocarcinoma associated with paraneoplastic cutaneous vasculitis: hypereosinophilic syndrome
with mixed cryoglobulinemia is an important sign of paraneoplastic syndrome. Rare Tumors 1:e42, 2009
Ogasawara H, Kageyama M, Yamaji K, Takasaki Y: The possibility that autoimmune disease can be induced by a molecular mimicry mechanism between autoantigen and human endogenous retrovirus. Lupus 19: 111-113, 2010
Shimane K, Kochi Y, Horita T, Ikari K, Amano H, Hirakata M, Okamoto A, Yamada R, Myouzen K, Suzuki A, Kubo M, Atsumi T, Koike T, Takasaki Y, Momohara S, Yamanaka H, Nakamura Y, Yamamoto K: The association of a nonsynonymous single-nucleotide polymorphism
in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population. Arthritis Rheum 62: 574-579, 2010
Matsuyama N, Morimoto S, Tokano Y, Amano H, Nozawa K, Isonuma H, Hashimoto H, Takasaki Y: The Long-Term Prognosis of Lupus Nephritis Patients Treated with Intravenous Cyclophosphamide. Inter Med 49: 823-828, 2010
Ito I, Kawasaki A, Ito S, Kondo Y, Sugihara M, Horikoshi M, Hayashi T, Goto D, Matsumoto I, Tsutsumi A, Takasaki Y, Hashimoto H, Matsuta K, Sumida T, Tsuchiya N: Replication of association between FAM167A(C8orf13)-BLK region and rheumatoid arthritis in
a Japanese population. Ann Rheum Dis 69: 936-937, 2010
Nakano S, Morimoto S, Suzuki S, Watanabe T, Amano H, Takasaki Y: Up-regulation of the endoplasmic reticulum transmembrane protein UNC93B in the B cells of patients with active systemic lupus erythematosus. Rheumatology 49: 876-881, 2010
Kon T, Yamaji K, Sugimoto K, Ogasawara M, Kenpe K, Ogasawara H, Yang KS, Tsuda H, Matsumoto T, Hashimoto H, Takasaki Y: Investigation of pathological and clinical features of lupus nephritis in 73 autopsied cases with systemic lupus erythematosus. Mod
Rheumatol 20: 168-177, 2010
Ando S, Amano H, Amano E, Minowa K, Watanabe T, Nakano S, Nakiri Y, Morimoto S, Tokano Y, Lin Q, Hou R, Ohtsuji M, Tsurui H, Hirose S, Takasaki Y: FTY720 exerts a survival advantage through the prevention of end-stage glomerular inflammation in lupus-prone
BXSB mice. Biochem Biophys Res Commun 94: 804-810, 2010
Kawasaki A, Ito I, Ito S, Hayashi T, Goto D, Matsumoto I, Takasaki Y, Hashimoto H, Sumida T, Tsuchiya N: Association of TNFAIP3 Polymorphism with Susceptibility to Systemic Lupus Erythematosus in a Japanese Population. J Biomed Biotech 2010: Article ID
207578 1-5, 2010
Toyama S, Tamura N, Haruta K, Karakida T, Mori S, Watanabe T, Yamori T, Takasaki Y: Inhibitory effects of ZSTK474, a novel phosphoinositide 3-kinase inhibitor, on osteoclasts and collagen-induced arthritis in mice. Arthritis Res Ther 12: R92 1-11, 2010
Kawasaki A, Ito S, Furukawa H, Hayashi T, Goto D, Matsumoto I, Kusaoi M, Ohashi J, Graham RR, Matsuta K, Behrens TW, Tohma S, Takasaki Y, Hashimoto H, Sumida T, Tsuchiya N: Association of TNFAIP3 interacting protein 1, TNIP-1 with systemic lupus erythematosus
in a Japanese population: a case-control association study. Arthritis Res Ther 12: R174, 2010.
Sekiya F, Yamaji K, Yang K, Tsuda H, Takasaki Y: Investigation of occurrence of osteonecrosis of the femoral head after increasing corticosteroids in patients with recurring systemic lupus erythematosus. Rheumatol Int 30: 1587-1593, 2010
Morimoto S, Watanabe T, Lee S, Amano H, Kanmaru Y, Ohsawa I, Tomino Y, Takasaki Y: Improvement of rapidly progressive lupus nephritis associated MPO-ANCA with tacrolimus. Mod Rheumatol 20: 291-294, 2010
Kawasaki M, Fujishiro M, Yamaguchi A, Nozawa K, Kaneko H, Takasaki Y, Takamori K, Ogawa H, Sekigawa I: Fluctuations in the gene expression of peripheral blood mononuclear cells between the active and inactive phases of systemic lupus erythematosus. Clin
Exp Rheumatol 28:311-317, 2010
Ogasawara M, Tamura N, Onuma S, Kusaoi M, Sekiya F, Matsudaira R, Kempe K, Yamaji K, Takasaki Y: Observational cross-sectional study revealing less aggressive treatment in Japanese elderly than nonelderly patients with rheumatoid arthritis. J Clin Rheumatol
16: 370-374, 2010
Otaki N, Chikazawa M, Nagae R, Shimozu Y, Shibata T, Ito S, Takasaki Y, Fujii J, Uchida K: Identification of a lipid peroxidation product as the source of oxidation-specific epitopes recognized by anti-DNA autoantibodies. J Biol Chem 285:33834-33842,
2010
Shen N, Fu Q, Deng Y, Qian X, Zhao J, Kaufman KM, Wu YL, Yu CY, Tang Y, Chen JY, Yang W, Wong M, Kawasaki A, Tsuchiya N, Sumida T, Kawaguchi Y, Howe HS, Mok MY, Bang SY, Liu FL, Chang DM, Takasaki Y, Hashimoto H, Harley JB, Guthridge JM, Grossman JM,
Cantor RM, Song YW, Bae SC, Chen S, Hahn BH, Lau YL, Tsao BP: Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus. Proc Natl Acad Sci USA 107:15838-15843, 2010
Sekigawa I, Fujishiro M, Yamaguchi A, Kawasaki M, Inui A, Nozawa K, Takasaki Y, Takamori K, Ogawa H: A new hypothesis of the possible mechanisms of gender differences in systemic lupus erythematosus. Clin Exp Rheumatol 28: 419-423, 2010
Minowa K, Amano H, Nakano S, Ando S, Watanabe T, Nakiri Y, Amano E, Tokano Y,Morimoto S, Takasaki Y: Elevated serum level of circulating syndecan-1(CD138)in active systemic lupus erythematosus. Autoimmunity 44: 357-362, 2011
Koga M, Kawasaki A, Ito I, Furuya T, Ohashi J, Kyogoku C, Ito S, Hayashi T, Matsumoto I, Kusaoi M, Takasaki Y, Hashimoto H, Sumida T, Tsuchiya N: Cumulative association of eight susceptibility genes with systemic lupus erythematosus in a Japanese female
population. SourceJ Hum Genet 56: 503-507. 2011
Kawamoto T, Abe Y, Ito J, Makino F, Kojima Y, Usui Y, Ma J, Morimoto S, Yagita H, Okumura K, Akiba H, Takasaki Y: Anti-T cell immunoglobulin and mucin domain-2 monoclonal antibody exacerbates collagen-induced arthritis by stimulating B cells. Arthritis
Res Ther13: R47, 2011
Kida I, Kobayashi S, Takeuchi K, Tsuda H, Hashimoto H, Takasaki Y: Antineutrophil cytoplasmic antibodies against myeloperoxidase, proteinase 3, elastase, cathepsin G and lactoferrin in Japanese patients with rheumatoid arthritis. Mod Rheumatol 21: 43-50,
2011
Kawasaki1 A, Furukawa H,Kondo Y, Ito S , Hayashi T, Kusaoi M, Matsumoto I,Tohma S, Takasaki Y, Hashimoto H, Sumida T,Tsuchiya N: TLR7 single-nucleotide polymorphisms in the 3' untranslated region and intron 2 independently contribute to systemic lupus
erythematosus in Japanese women: a case-control association study. Arthritis Res Ther 13: R41, 2011
Hikami K, Kawasaki A, Ito I, Koga M, Ito S, Hayashi T, Matsumoto I, Tsutsumi A, Kusaoi M, Takasaki Y, Hashimoto H, Arinami T, Sumida T, Tsuchiya N: Association of a Functional Polymorphism in the 3'-Untranslated Region of SPI1 With Systemic Lupus Erythematosus.
Arthritis Rheum 63: 755-763, 2011
Yamada R, Nozawa K, Yoshimine T, Takasaki Y, Ogawa H, Takamori K, Sekigawa I: A Case of Thrombotic Thrombocytopenia Purpura Associated with Systemic Lupus Erythematosus: Diagnostic Utility of ADAMTS-13 Activity. Autoimmune Dis: 2011; 483642, 2011
Hotatsu K, Yamaji K, Yamada R, Oda K, Kageyama M, Kusaoi M, Onuma S, Kawamoto T, Sugimoto K, Sekiya F, Kon T, Ogasawara M, Kempe K, Tsuda H, Takasaki Y: Effect of Various Aniticoagulant Agents on Large-Volume Leukocytapheresis Using New Cellsorba CS-180S
Filter. Ther Apher Dial 15:355-359, 2011
Matsudaira R, Tamura N, Sekiya F, Ogasawara M, Yamanaka K, Takasaki Y: Anti-Ro/SSA Antibodies Are an Independent Factor Associated with an Insufficient Response to Tumor Necrosis Factor Inhibitors in Patients with Rheumatoid Arthritis. J Rheumatol 38:2346-2354,
2011
Nawata M, Matsushita M, Matsudaira R, Yamada H, Kaneda K, Asano M, Yamanaka K, Murakami A, Takasaki Y: Clinical Significance of Anti-U1 RNP Antibodies Recognizing The Conformation Structure on U1 RNA/70-kd Protein Complex in Patients with Mixed Connective
Tissue Disease. Juntendo Med Journa l57:477-487, 2011
Miyano G, Hayashi T, Arakawa A, Nawata M, Takasaki Y, Tanaka N, Lane GJ, Kato Y, Yamataka A, Okazaki T: Choledochal cyst and systemic lupus erythematosus. Surg Int 27:111-113, 2011
Kawasaki M, Fujishiro M, Yamaguchi A, Nozawa K, Kaneko H, Takasaki Y, Takamori K, Ogawa H, Sekigawa I: Possible role of the JAK/STAT pathways in the regulation of T cell-interferon related genes in systemic lupus erythematosus. Lupus 20: 1231-1239, 2011
190) Miyano G, Hayashi T, Arakawa A, Nawata M, Takasaki Y, Tanaka N, Lane GJ, Kato Y, Yamataka A, Okazaki T: Choledochal cyst and systemic lupus erythematosus. Pediatr surgint 27: 111-113, 2011
191) Ogasawara M, Tamura N, Kageyama M, Onuma S, Kusaoi M, Toyama S, Sekiya F, Matsudaira R, Nawata M, Tada K, Matsushita M, Kempe K, Amano H, Morimoto S, Yamaji K, Takasaki Y: Single-center, retrospective analysis of efficacy and safety of tacrolimus
as a second-line DMARD in combination therapy and the risk factors contributing to adverse events in 115 patients with rheumatoid arthritis. Clin Rheumatol 31: 251-257, 2012
Fujishiro M, Yamaguchi A, Kawasaki M, Nozawa K, Takasaki Y, Takamori K, Ogawa H, Endo K, Ng PS, Takehara K, Sekigawa I: The detection of plasma levels of connective tissue growth factor in rheumatoid arthritis patients. Clin Exp Rheumatol 30:145-146,
2012
Ogasawara M, Kageyama M, Kusaoi M, Onuma S, Kon T, Sekiya F, Sugimoto K, Matsudaira R, Matsushita M, Tada K, Kempe K, Yamaji K, Tamura N, Takasaki Y: Recent trends in use of nonbiologic DMARDs and evaluation of their continuation rates in single and dual
combination therapies in rheumatoid arthritis patients in Japan. Mod Rheumtol 22: 831-836, 2012
Yamaguchi A, Nozawa K, Fujishiro M, Kawasaki M, Takamori K, Ogawa H, Sekigawa I, Takasaki Y: Estrogen inhibits apoptosis and promotes CC motif chemokine ligand 13 expression on synovial fibroblasts in rheumatoid arthritis. Rheumatol Int 34: 852-857, 2012
Okada Y, Shimane K, Kochi Y, Tahira T, Suzuki A, Higasa K, Takahashi A, Hirota T, Atsumi A, Ishii T, Okamoto A, Fujio K, Hirakata M, Amano H, Kondo Y, Ito S, Takada K, Mimori A, Saito K, Kamachi M, Kawaguchi Y, Ikari K, Mohammed ow, Matsuda K, Terao C,
Ohmura K, Myouzen K, Hosono N, Tsunoda T, Nishimoto N, Minori T, Matsuda F, Tanaka Y, Sumida T, Yamanaka H, Takasaki Y, Koike T, Horiuchi T, Hayashi K, Kubo M, Kamatani N, Yamada R, Nakamura Y, Yamamoto K: A Genome-Wide Association Study Identified AFF1
as a Susceptibility Locus for Systemic Lupus Eyrthematosus in Japanese. PLoS Genetics 8;e1002455, 2012
Ogasawara M, Murayama G, Yamada Y, Nemoto T, Kageyama M, Toyama S, Kusaoi M, Onuma S, Kon T, Sekiya F, Sugimoto K, Matsudaira R, Matsushita M, Tada K, Kempe K, Yamaji K, Tamura N, Takasaki Y: Autofeedback from Ultrasound Images Provides Rapid Improvement
in Palpation Skills for Identiffying Joint Swelling in Rheumatoid Arthritis. J Rheumatol 39: 1207-1214, 2012
Fujishiro M, Nozawa K, Kawasaki M, Yamaguchi A, Iwabuchi K, Yanagida M, Suzuki F, Miyazawa K, Fukui H, Kaneko K, ogawa H, Takamori K, Takasaki Y, Sekigawa I: Regenerating gene(REG) 1 alpha promotes pannus progression in patients with rheumatoid arthritis.
Mod Rheumatol 22:228-237, 2012
Ikeda T, Toyama S, Ogasawara M, Amano H, Takasaki Y, Morita H, Ishizuka T: Rheumatoid arthritis complicated with immunodeficiency-associated lymphoproliferative disorders during treatment with adalimumab. Mod Rheumatol 22: 458-462, 2012
Yamaguchi A, Nozawa K, Fujishiro M, Kawasaki M, Suzuki F, Takamori K, Ogawa H, Takasaki Y, Sekigawa I: CC motif chemokine ligand 13 is associated with rheumatoid arthritis pathogenesis. Mod Rheumatol 23: 856-863, 2012
Yanagida M, Jung G, Tanaka Y, Sone S, Fujishiro M, Ikeda K, Nozawa K, Kaneko H, Takasaki Y, Ogawa H, Takamori K, Sekigawa I: Serum proteome analysis in patients with rheumatoid arthritis receving therapy with etanercept, a chimeric tumor necrosis factor-alpha
receptor. Int J Rheumatic Dis 15: 486-495, 2012
Kusaoi M, Yamaji K, Murayama G, Yasui M, Yamada R, Hishinuma R, Nemoto T, Hohtatsu K, Kageyama M, Kawamoto T, Sugimoto K, Sekiya F, Kon T, Ogasawara M, Kempe K, Tsuda H, Takasaki Y: Gene expression analysis using a high-resolutiom DNA microarray of peripheral
whole blood immediately before and after leukocytapheresis for rheumatoid arthritis. Ther Apher Dial 16: 456-466, 2012
Kawasaki A, Furukawa H, Kondo Y, Ito S, Hayashi T, Kusaoi M, Matsumoto I, Tohma S, Takasaki Y, Hashimoto H, Sumida T, Tsuchiya N: Association of PHRF1-IRF7 region polymorphism with clinical manifestations of systemic lupus erythematosus in a Japanese
population. Lupus 21: 890-895, 2012
Haruta K, Mori S, Tamura N, Sasaki A, Nagamine M, Yaguchi S, Kamachi F, Enami J, Kobayashi S, Yamori T, Takasaki Y: Inhibitory effects of ZSTK474, a phosphatidylinositol 3-kinase inhibitor, on adjuvant-induced arthritis in rats. Inflamm Res 61: 551-562.
2012
Yanagida M, Kawasaki M, Fujishiro M, Miura M, Ikeda K, Nozawa K, Kaneko H, Morimoto S, Takasaki Y, Ogawa H, Takamori K, Sekigawa I: Serum proteome analysis in patients with rheumatoid arthritis receiving therapy with tocilizumab: an anti-interleukin-6
receptor antibody. Biomed Res Int 2013: 607137. 2013
Anami A, Fukushima K, Takasaki Y, Sumida T, Waguri M, Wake N, Murashima A: The predictive value of anti-SS-A antibodies titration in pregnant women with fetal congenital heart block. Mod Rheumatol 23: 653-658, 2013
Nozawa K, Fujishiro M, Kawasaki M, Yamaguchi A, Ikeda K, Morimoto S, Iwabuchi K, Yanagida M, Ichinose S, Morioka M, Ogawa H, Takamori K, Takasaki Y, Sekigawa I: Inhibition of Connective Tissue Growth Factor Ameliorates Disease in a Murine Model of Rheumatoid
Arthritis. Arthritis Rheum 65: 1477-1486, 2013
Kawano S, Lin Q, Amano H, Kaneko T, Nishikawa K, Tsurui H, Tada K, Nishimura H, Takai T, Shirai T, Takasaki Y, Hirose S: Phenotype conversion form rheumatoid arthritis to systemic lupus erythematosus by introduction of Yaa mutation into FcɣRIIB-deficient
G57BL/6 mice. Eur.J.Immunol 43: 770-778, 2013
Furukawa H, Kawasaki A, Shimada K, Matsui T, Ikenaka T, Hashimoto A, Okazaki Y, Takaoka H, Futami H, Komiya A, Kondo Y, Ito S, Hayashi T, Matsumoto I, Kusaoi M, Takasaki Y, Nagai T, Hirohata S, Setoguchi K, Sudo A, Nagaoka S, Kono H, Okamoto A, Chiba
N, Suematsu E, Fukui N, Hashimoto H, Sumida T, Ono M, Tsuchiya N, Tohma S: Association of a single nucleotide polymorphism in the SH2D1A intronic region with systemic lupus erythematosus. Lupus 22: 497-503, 2013
Shimane K, Kochi Y, Suzuki A, Okada Y, Ishii T, Horita T, Saito K, Okamoto A, Nishimoto N, Myouzen K, Kubo M, Hirakata M, Sumida T, Takasaki Y, Yamada R, Nakamura Y, Kamatani N, Yamamoto K: An association analysis of HLA-DRB1 with systemic lupus erythematosus
and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes. Rheumatology 52: 1172-1182, 2013
Murayama G, Ogasawara M, Nemoto T, Yamada Y, Ando S, Minowa K, Kon T, Tada K, Matsushita M, Yamaji K, Tamura N, Takasaki Y: Clinical miscount of involved joints denotes the need for ultrasound complementation in usual practice for patients with rheumatoid
arthritis. Clin Rheumatol 31: 506-514, 2013
Inami Y, Yamaji K, Sato M, Gohda T, Io H, Nawata M, Hamada C, Takasaki Y, Tomino Y: Effects of dialysis on the pharmacokinetics of salazosulfapyridine. Rheumatol Int 33:535-539, 2013
Nemoto T, Ogasawara M, Matsuki Y, Myrayama G, Yamada Y, Sugisaki N, Ando S, Minowa K, Kon T, Tada K, Matushita M, Yamaji K, Tamura N, Takasaki Y: Can routine clinical measures predict ultrasound-determined synovites and remission in rheumatoid arthritis
patients? Clin Rheumatol 32: 54-60, 2013
Abe Y, Kamachi F, Kawamoto T, Makino F, Ito J, Kojima Y, Moustapha Ael D, Usui Y, Yagita H, Takasaki Y, Okumura K, Akiba H: TIM-4 has dual function in the induction and effector phases of murine arthritis. J lmmunol 191: 4562-4572, 2013
Gorai M, Ogasawara M, Matsuki Y, Yamada Y, Murayama G, Sugisaki N, Nemoto T, Ando S, Minowa K, Kon T, Tada K, Matsushita M, Yamaji K, Tamura N, Takasaki Y: Weigting with the Lansbury articular index improves the correlation of ultrasound score with serum
matrix metalloproteinase-3 level in rheumatoid arthritis patients. Mod Rheumatol 24: 315-919, 2014
Yamada R, Kusaoi M, Murayama G, Yasui M, Hishinuma R, Nemoto T, Hohtatsu K, Kageyama M, Kawamoto T, Sugimoto K, Sekiya F, Kon T, Ogasawara M, Kempe K, Yamaji K, Tsuda H, Takasaki Y: Reduction in bradykinin generation during leukocytapheresis using novel
cellsorba(TM) CS-180S: Effects of changing the filling solution. J Clin Apher 29: 90-96, 2014
Kaneko T, Amano H, Kawano S, Minowa K, Ando S, WatanabeT, Nakano S, Suzuki J, Morimoto S, Tokano Y, Takasaki Y: Increased serum concentration of BAFF/APRIL and IgA2 subclass in patients with mixed connective tissue disease complicated by interstitial
lung disease. Mod Rheumatol 24: 310-315, 2014
Masuda H, Miyazaki T, Shimada K, Tamura N, Matsudaira R, Yoshihara T, Ohsaka H, Sai E, Matsumori R, Fukao K, Hiki M, Kume A, Kiyanagi T, Takasaki Y, Daida H: Disease duration and severity impacts on long-term cardiovascular events in Japanese patients
with rheumatoid arthritis. J Cardiol 64: 566-570, 2014
Nakashima R, Imura Y, Hosono Y, Aeto M, Murakami A, Watanabe K, Handa T, Mishima M, Hirakata M, Takeuchi T, Fujio K, Yamamoto K, Kohsaka H, Takasaki Y, Enomoto N, Suda T, Chida K, Hisata S, Nukiwa T, Mimori T: The multicenter study of a new assay for
simultaneous detection of multiple anti-aminoacyl-tRNA synthetases in myositis and interstitial pneumonia. PLoS One 9: e85062, 2014
Doe K, Nozawa K, Hiruma K, Yamada Y, Matsuki Y, Nakano S, Ogasawara M, Nakano H, Ikeda T, Ikegami T, Fujishiro M, Kawasaki M, Ikeda K, Amano H, Morimoto S, Ogawa H, Takamori K, Sekigawa I, Takasaki Y: Antibody against chromatin assembly factor-1 is a
novel autoantibody specifically recognized in systemic lupus erythematosus. Lupus 23: 1031-1041, 2014
Doe K, Nozawa K, Okada T, Tada K, Yamaji K, Tamura N, Takasaki Y: Usefulness of minor salivary gland biopsy in the diagnosis of IgG4-related disease: a case report. Int J Clin Exp Pathol 7: 2673-2677, 2014
Sada K, Yamamura M, Harigai M, Fujii T, Dobashi H, Takasaki Y, Ito S, Yamada H, Wada T, Hirahashi J, Arimura Y, Makino H, and for the Reserch Committee on Intractable Vasculitides, the Ministry of Health, Labour and Welfare of Japan: Classification and
characteristics of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis in a nationwide, prospective, inception cohort study. Arthritis Res Ther 16: R101, 2014
Kawasaki A, Furukawa H, Nishida N, Warabi E, Kondo Y, Ito S, Matsumoto I, Kusaoi M, Amano H, Suda A, Nagaoka S, Setoguchi K, Nagai T, Hirohata S, Shimada K, Sugii S, Okamoto A, Chiba N, Suematsu E, Ohno S, Katayama M, Okamoto A, Kono H, Tokunaga K, Takasaki
Y, Hashimoto H, Sumida T, Tohma S, Tsuchiya N: Association of Functional Polymorphisms in interferon Regulatory Factor 2(IRF2) with Susceptibility to Systemic Lupus Erythematosus: A Case-Control Association Study. PLOS ONE 9: e109764, 2014
223）Suzuki S, Morimoto S, Fujishiro M, Kawasaki M, Hayakawa K, Miyashita T, Ikeda K, Miyazawa K, Yanagida M, Takamori K, Ogawa H, Sekigawa I, Takasaki Y: Inhibition of the insulin-like growth factor system is a potential therapy for rheumatoid arthritis.
Autoimmunity 48: 251-258, 2014
Furukawa H, Kawasaki A, Oka S, Ito I, Shimada K, Sugii S, Hashimoto A, Komiya A, Fukui N, Kondo Y, Ito S, Hayashi T, Matsumoto I, Kusaoi M, Amano H, Nagai T,Hirohata S, Setoguchi K, Kono H, Okamoto A, Chiba N, Suematsu E, Katayama M,Migita K, Suda A,
Ohno S, Hashimoto H, Takasaki Y, Sumida T, Nagaoka S, Tsuchiya N, Tohma S. Human Leukocyte Antigens and Systemic Lupus Erythematosus: A Protective Role for the HLA-DR6 Alleles DRB1*13:02 and *14:03. PLoS One. 3;9, 2014
Nozawa K, Fujishiro M, Takasaki Y, Sekigawa I: Inhibition of rheumatoid arthritis by blocking connective tissue growth factor. World J Orthop 18: 653-659, 2014
Tokai N, Ogasawara M, Gorai M, Matsuki Y, Yamada Y, Murayama G, Sugisaki N, Nemoto T, Ando S, Minowa K, Kon T, Tada K, Matsushita M, Yamaji K, Tamura N, Makino S, Takasaki Y: Predictive value of bone destruction and duration of clinical remission for
subclinical synovitis in rheumatoid arthritis patients. Mod Rheumatol 25: 540-545, 2015
Doe K, Nozawa K, Hirai T, Tsushima H, Hayashi E, Hiruma K, Ando S, Nakano S, Kon T, Amano H, Yamaji K, Tamura N, Takasaki Y: Second-to-fourth Digit Ratio in Systemic Lupus Erythematosus. J Rheumatol 42: 826-828, 2015
Nakano S, Morimoto S, Suzuki S, Tsushima H, Yamanaka K, Sekigawa I, Takasaki Y: Immunoregulatory role of IL-35 in T cells of patients with rheumatoid arthritis. Rheumatology 54: 1498-1506, 2015
Yamazaki H, Sakai R, Koike R, Miyazaki Y, Tanaka M, Nanki T, Watanabe S, Yasuda S, Kurita T, Kaneko Y, Tanaka Y, Nishioka Y, Takasaki Y, Nagasaka K, Nagasawa H, Tohma S, Dohi M, Sugihara T, Sugiyama H, Kawaguchi Y, Inase N, Ochi S, Hagiyama H, Hitoshi
K, Miyasaka N, Harigai M, for the PREVENT Study Group: Assessment of Risks of Pulmonary Infection During 12 Months Following Immunosuppressive Treatment for Active Connective Tissue Diseases:A Large-scal Prospective Cohort Study. J Rheumatol 42: 614-622,
2015
Minowa K, Ogasawara M, Murayama G, Gorai M, Yamada Y, Nemoto T, Matsuki Y, Sugisaki N, Ando S, Kon T, Tada K, Matsushita M, Yamaji K, Tamura N, Takasaki Y: Predictive grade of ultrasound synovitis for diagnosing rheumatoid arthritis in clinical practice
and the possible difference between patients with and without seropositivity. Mod Rheumatol , 2015(inpress)
Ishiyama K, Yashiro T, Nakano N, Kasakura K, Miura R, Hara M, Kawai F, Maeda K, Tamura N, Okumura K, Ogawa H, Takasaki Y, Nishiyama C: Involvement of PU.1 in NFATc1 promoter function in osteoclast development. Allergol Int 64: 241-247, 2015
Honda D, Tsueshita K, Ohsawa I, Miyashita T, Inoshita H, Shimamoto M, Horikoshi S, Motimoto S, Takasaki Y, Tomino Y: Clinical Significance of Renal Interstitial Fibrosis in Patients with Lupus Nephritis. Juntendo Mde J 61: 418-425, 2015
Takasaki Y: Clinical significance of antibodies to PCNA. Jpn J Rheumatol 8: 1-12, 1998
Takasaki Y, Kaneda K, Takeuchi K, Yano T, Hashimoto H: Antibodies to PCNA and Ki - A linked set of autoimmune response associated with celluar function of target antigens. Autoimmunity, Autoantigens, Autoantibodies 1: 88-109, 2000
Sekigawa I, Kawasaki M, Ogasawara H, Kaneda K, Kaneko H, Takasaki Y, Ogawa H: DNA methylation: its contribution to systemic lupus erythematosus. Clin Exp Med 6: 99-106, 2006
Sekigawa I, Fujishiro M, Yamaguchi A, Kawasaki M, Inui A, Nozawa K, Takasaki Y, Takamori K, Ogawa H: A new hypothesis of the possible mechanisms of gender differences in systemic lupus erythematosus. Clin Exp Rheumatol 28:419-23, 2010
Nozawa K, Fujishiro M, Takasaki Y, Sekigawa I: Inhibition of rheumatoid arthritis by blocking connective tissue growth factor. World J Orthop 5: 653-659, 2014
Takasaki Y, Yasuma M, Kodama A, Hashimoto H, Hirose S: Enzyme-linked-immunosorbent-assay for anti-Sm antibody and clinical significance of immunoglobulin class, in Mixed connective tissue disease and anti-nuclear antibodies, Excepta Medica ICS 719. Edited
by R Kasukawa and G.C. Sharp, Elsevier Science Publishers, Netherlands, 1987, pp 121-126.
Takasaki Y, Tsuda H, Shiozawa K, Yamagata J, Hashimoto H, Hirose S: Plasma exchange (Plasmapheresis) in treatment of mixed connective tissue disease, in Mixed connective tissue disease and anti-nuclear antibodies, Excepta Medica ICS 719. Edited by R Kasukawa,
G.C. Sharp, Elsevier Science Publishers, Netherlands, 1987, pp337-341.
Kasukawa R, Tojo T, Miyawaki S, Yoshida H, Tanimoto K, Nobunaga M, Suzuki T, Takasaki Y, Tamura T: Preliminary diagnostic criteria for classification of mixed connective tissue disease, in Mixed connective tissue disease and anti-nuclear antibodies, Excepta
Medica ICS 719. Edited by R Kasukawa, G.C. Sharp, Elsevier Science Publishers, Netherlands, 1987, pp41-47.
Nakane PK, Moriuchi T, Koji T, Sekino M, Izumi S, Matsumoto K, Daidoji H, Takasaki Y: Proliferating cell nuclear antigen (PCNA/cyclin), in Recent Advances in Immunopathology. Edited by Hamashima Y, Yamashiro Printing,Kyoto,1987, PP179-197
Takasaki Y, Tan EM: Autoantibodies to PCNA, in SectionC ; Clinical significance of autoantibodies; Manual of biological markers of disease: Edited by Maini RN,Van Venrooij W, Kluwer Academic Publisher, 1996, Netherlands, pp AMAN-C2.4/1- AMAN-C2.4/11
Sekigawa I, Lee S, Takasaki Y, Hashimoto H: Interleukin(Il)-16:A useful indicator of the disease activity of systemic lupus erythematosus (SLE). Medical Updates, on Therapy, Diagnosis and Prevention. American International Health Council, Pittburg, 2000,
156-157
Nozawa K, Satoh M, Cha S, Takasaki Y, Edward K.l.Chan: Autoantibodies and Autoantigens in Sjogren's Syndrome. Sjogren's Syndrome, Edited by Robert I, Carla M, Springer, 2011, pp111-132
Nozawa k, Fujishiro M, Takasaki Y, Ogawa H, Sekigawa I: Mechanism of Disease Amelioration on Infliximab Treatment: Novel Effecter Molecules for Pathogenesis of Rheumatoid Arthritis. Infliximab, Editors A,Acevedo and M.Gaitan, Nova Science Publishers,America,
2012, 167-176
